Parkinson’s disease (PD) is a disorder of the central nervous system that affects movement, often including tremors. This causes a gradual loss of muscle control. While treatment can help, there is no known cure.
Those with the disease have nerve cell damage in their brains which causes dopamine levels to drop. Dopamine is an essential neurotransmitter in the human brain, responsible for transmitting information among neurons and helping with the regulation of various functions, such as movement and emotional responses.
While Parkinson’s itself is not fatal, its complications can be serious. The CDC rated complications from Parkinson’s as the 14th cause of death in the United States.
Two of the most famous individuals with Parkinson’s’ are Michael J. Fox and Muhammad Ali.
A 2017 study concluded that Cannabidiol might help the movement impairments in Parkinson’s and Alzheimer’s disease by interacting with a receptor known as GPR6.
These studies suggest that Cannabidiol could potentially slow the progression of Parkinson’s by providing neuroprotective effects. Cannabidiol is shown to suppress the excitotoxicity, glial activation and oxidative injury that cause the degeneration of the dopamine-releasing neurons.
A 2020 publication out of Brazil in the Journal of Psychopharmacology has some wonderful news for those of you with Parkinson’s Disease. The report finds that acute CBD administration at a dose of 300 mg decreased anxiety in patients with PD, and there was also decreased tremor amplitude in an anxiogenic situation.