Multiple Sclerosis, or MS, is characterized by the long-lasting damage to the nerve cells in the brain and spinal cord.
CBD studies suggest that the anti-inflammatory effects of CBD can benefit patients with MS, aiding in pain reduction and slowing the progression of this disease.
Outside the U.S. a drug called Sativex by GW Pharmaceuticals is used to treat muscle spasms associated with multiple sclerosis. Sativex contains a 1:1 ratio of THC and CB, distributed by an oromucosal spray.
A 2013 study suggests that Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: a role for A2A receptors.
A 2010 study concluded that CBD reduced the severity of symptoms associated with spasticity.
While CBD is not yet FDA-approved for any condition, many studies and user testimonies have shown promising results for a variety of indications.
- Sativex for the management of multiple sclerosis symptoms
- THC & CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis
- Clinical efficacy and effectiveness of Sativex, a combined cannabinoid medicine, in multiple sclerosis-related spasticity
- CBD provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors
- Oromucosal delta9-THC/CBD for neuropathic pain associated with multiple sclerosis
- Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis
- Sativex long-term use: An open-label trial in patients with spasticity due to multiple sclerosis
- A double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis
- Meta-analysis of cannabis-based treatments for neuropathic and multiple sclerosis-related pain
- Sativex: Clinical efficacy and tolerability in the treatment of symptoms of multiple sclerosis and neuropathic pain
- Evaluating Sativex in Neuropathic Pain Management
- CBD counteracted the development of experimental MS
- CBD/THC Oromucosal Spray for Multiple Sclerosis-Related Resistant Spasticity in Daily Practice
- Neurological aspects of the medical use of CBD